Factors That Affect Your Risk of Getting Very Sick from COVID-19 | CDC

Vaccination

COVID-19 vaccines are safe and effective. Staying up to date with your COVID-19 vaccines is the best way to protect yourself and others around you from getting very sick, being hospitalized, or dying from COVID-19. Booster doses can give you additional protection. They can help enhance or restore protection that might have decreased over time.

People who are vaccinated with all recommended vaccine doses, including boosters, are far less likely to be hospitalized or die from COVID-19 than people the same age who have not been vaccinated or who are not up to date on their COVID-19 vaccines. However, even though vaccines reduce their risk, some people, particularly older adults with multiple underlying health conditions or people who are immunocompromised, can still get very sick from COVID-19.